Anti-MUC16 antibody(3B11); IgG1 Chimeric mAb
Product Sizes
10μg
£492.00
12-9636-10UG
100μg
£801.00
12-9636-100UG
About this Product
- SKU:
- 12-9636
- Additional Names:
- CA125
- translate.label.attr.clone:
- 3B11
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight; O-glycosylated proteins that play an important role in forming a protective mucous barrier; and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus; a large tandem repeat domain; and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated; while the repeat region contains 156 amino acid repeats unit that are rich in serines; threonines; and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules; leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain; and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier; protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers; with higher expression levels associated with poorer outcomes. [provided by RefSeq; May 2017]
- Host:
- Rabbit
- Isotype:
- Rabbit/Human Fc chimeric IgG1
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
