Anti-SEMA4D antibody(11G2); IgG1 Chimeric mAb
Product Sizes
10μg
£492.00
12-9631-10UG
100μg
£801.00
12-9631-100UG
About this Product
- SKU:
- 12-9631
- Additional Names:
- A8;BB18;GR3;CD100;C9orf164;CD100;SEMAJ
- translate.label.attr.clone:
- 11G2
- Clonality:
- Monoclonal
- Extra Details:
- Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed:19788569). Promotes the migration of cerebellar granule cells (PubMed:16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed:8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2; SRC; and the phosphatidylinositol 3-kinase-AKT pathway (PubMed:16055703).[UniProtKB/Swiss-Prot Function]
- Host:
- Rabbit
- Isotype:
- Rabbit/Human Fc chimeric IgG1
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
