Anti-SELPLG antibody(68H10); IgG1 Chimeric mAb
Product Sizes
10μg
£492.00
12-9620-10UG
100μg
£801.00
12-9620-100UG
About this Product
- SKU:
- 12-9620
- Additional Names:
- PSGL-1;PSGL1;CD162;Selectin P ligand
- translate.label.attr.clone:
- 68H10
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Isotype:
- Rabbit/Human Fc chimeric IgG1
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
