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Antibodies

Anti-IGF-1R antibody(DMC721); IgG1 Chimeric mAb

Product Sizes
10 µg
£490.00
12-9488-10UG
100 µg
£801.00
12-9488-100UG
About this Product
SKU:
12-9488
Additional Names:
CD221; IGFIR; IGFR; JTK13
translate.label.attr.clone:
DMC721
Clonality:
Monoclonal
Extra Details:
Description :Anti-IGF-1R antibody(DMC721); IgG1 Chimeric mAbThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq; May 2014]
Host:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg