Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb
Product Sizes
10 µg
£490.00
12-9460-10UG
100 µg
£801.00
12-9460-100UG
About this Product
- SKU:
- 12-9460
- Additional Names:
- Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO
- translate.label.attr.clone:
- DMC484
- Clonality:
- Monoclonal
- Extra Details:
- Description :Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAbThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation; invasion; and:or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq; Nov 2015]
- Host:
- Rabbit
- Isotype:
- Rabbit/Human Fc chimeric IgG1
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
