Anti-PMEL antibody(DMC420); IgG1 Chimeric mAb
Product Sizes
10 µg
£490.00
12-9414-10UG
100 µg
£801.00
12-9414-100UG
About this Product
- SKU:
- 12-9414
- Additional Names:
- D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
- translate.label.attr.clone:
- DMC420
- Clonality:
- Monoclonal
- Extra Details:
- Description :Anti-PMEL antibody(DMC420); IgG1 Chimeric mAbThis gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes; which are the melanin-producing organelles in melanocytes; and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Isotype:
- Rabbit/Human Fc chimeric IgG1
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
