Anti-CD45 antibody(DM193); Rabbit mAb
Product Sizes
100 µg
£801.00
12-9364-100UG
About this Product
- SKU:
- 12-9364
- Additional Names:
- B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
- translate.label.attr.clone:
- DM193
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported.
- Host:
- Rabbit
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
