Biotinylated Anti-BAFF-R antibody(DM143); Rabbit mAb
Product Sizes
10 µg
£526.00
12-9316B-10UG
100 µg
£1002.00
12-9316B-100UG
About this Product
- SKU:
- 12-9316B
- Additional Names:
- BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin
- translate.label.attr.clone:
- DM143
- Clonality:
- Monoclonal
- Extra Details:
- B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- Host:
- Rabbit
- Isotype:
- IgG
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
