Anti-CSF1R antibody(DM107); Rabbit mAb
Product Sizes
100 µg
£801.00
12-9281-100UG
About this Product
- SKU:
- 12-9281
- Additional Names:
- CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR
- translate.label.attr.clone:
- DM107
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma.
- Host:
- Rabbit
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
