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Antibodies

Biotinylated Anti-IL5RA antibody(DMC393); IgG1 Chimeric mAb

Product Sizes
10 µg
£526.00
12-9246B-10UG
100 µg
£1002.00
12-9246B-100UG
About this Product
SKU:
12-9246B
Additional Names:
IL5Ra;CD125;IL-5 R alpha
translate.label.attr.clone:
DMC393
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3); colony stimulating factor 2 (CSF2:GM-CSF); and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding; and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin); which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Host:
Rabbit
Isotype:
IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody