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Antibodies

Anti-FOLR1 antibody(DMC391); IgG1 Chimeric mAb

Product Sizes
100 µg
£801.00
12-9244-100UG
About this Product
SKU:
12-9244
Additional Names:
FBP; FOLR; FRalpha
translate.label.attr.clone:
DMC391
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives; and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters; multiple transcription start sites; and alternative splicing; multiple transcript variants encoding the same protein have been found for this gene.
Host:
Rabbit
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2. Flow cytometry analysis of antigen binding of anti-human FOLR1 mAb. (A) Anti-human FOLR1 mAb does weakly bind to Jurkat cells that do not express FOLR1. (B) A clear peak shift of anti-human FOLR1 mAb was seen compared to the control when incubated with FOLR1-expressing Hela cells; indicating strong binding of anti-human FOLR1 mAb to FOLR1. Antibodies were incubated at 2 µg/mL.
Figure 2. Flow cytometry analysis of antigen binding of anti-human FOLR1 mAb. (A) Anti-human FOLR1 mAb does weakly bind to Jurkat cells that do not express FOLR1. (B) A clear peak shift of anti-human FOLR1 mAb was seen compared to the control when incubated with FOLR1-expressing Hela cells; indicating strong binding of anti-human FOLR1 mAb to FOLR1. Antibodies were incubated at 2 µg/mL.