Anti-GPC3 antibody(DMC371); IgG1 Chimeric mAb
Product Sizes
100 µg
£801.00
12-9239-100UG
About this Product
- SKU:
- 12-9239
- Additional Names:
- DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
- translate.label.attr.clone:
- DMC371
- Clonality:
- Monoclonal
- Extra Details:
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26; and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome; also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Sep 2009] References? Fu Ying;Urban Daniel J;Nani Roger R et al. Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.[J] .Hepatology; 2019; 70: 563-576. Zhang Yi-Fan;Ho Mitchell;Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.
- Host:
- Rabbit
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
