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Antibodies

Biotinylated Anti-IL5 antibody(DMC274); IgG1 Chimeric mAb

Product Sizes
10 µg
£526.00
12-9217B-10UG
100 µg
£1002.00
12-9217B-100UG
About this Product
SKU:
12-9217B
Additional Names:
IL-5;TRF;Interleukin-5;EDF
translate.label.attr.clone:
DMC274
Clonality:
Monoclonal
Extra Details:
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation; maturation; recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor; which is a heterodimer; whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2:GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4); interleukin 13 (IL13); and CSF2 . This gene; IL4; and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Host:
Rabbit
Isotype:
IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody