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Antibodies

Anti-CD112 antibody(DMC224); IgG1 Chimeric mAb

Product Sizes
100 µg
£801.00
12-9208-100UG
About this Product
SKU:
12-9208
Additional Names:
NECTIN2? HVEB? PRR2? PVRL2? PVRR2
translate.label.attr.clone:
DMC224
Clonality:
Monoclonal
Extra Details:
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus; and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Host:
Rabbit
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD112 mAb. (A) The antibody does not bind to MM.1S cells that do not express CD112. (B) A clear peak shift of the antibody was seen compared to the control when incubated with CD112-expressing MCF-7 cells; indicating strong binding of the antibody to CD112. Antibodies were incubated at 5 µg/mL.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD112 mAb. (A) The antibody does not bind to MM.1S cells that do not express CD112. (B) A clear peak shift of the antibody was seen compared to the control when incubated with CD112-expressing Huh7 cells; indicating strong binding of the antibody to CD112. Antibodies were incubated at 5 µg/mL.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD112 mAb. (A) The antibody does not bind to MM.1S cells that do not express CD112. (B) A clear peak shift of the antibody was seen compared to the control when incubated with CD112-expressing Huh7 cells; indicating strong binding of the antibody to CD112. Antibodies were incubated at 5 µg/mL.