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Antibodies

Anti-TREM2 antibody(DMC223); IgG1 Chimeric mAb

Product Sizes
100 µg
£801.00
12-9207-100UG
About this Product
SKU:
12-9207
Additional Names:
PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
translate.label.attr.clone:
DMC223
Clonality:
Monoclonal
Extra Details:
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
Host:
Rabbit
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2. Flow cytometry analysis of antigen binding of anti-human TREM2 mAb. (A) The antibody does not bind to CHO-S cells that do not express TREM2. (B) A clear peak shift of the antibody was seen compared to the control when incubated with TREM2-expressing THP-1 cells; indicating strong binding of the antibody to TREM2. Antibodies were incubated at 5 µg/mL.
Figure 2. Flow cytometry analysis of antigen binding of anti-human TREM2 mAb. (A) The antibody does not bind to CHO-S cells that do not express TREM2. (B) A clear peak shift of the antibody was seen compared to the control when incubated with TREM2-expressing THP-1 cells; indicating strong binding of the antibody to TREM2. Antibodies were incubated at 5 µg/mL.