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Antibodies

Anti-MSLN antibody(DM71); Rabbit mAb

Product Sizes
100 µg
£801.00
12-9058-100UG
About this Product
SKU:
12-9058
Additional Names:
MSLN; Mesothelin; MPF
translate.label.attr.clone:
DM71
Clonality:
Monoclonal
Extra Details:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products; megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas; ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed.
Host:
Rabbit
Immunogen:
Recombinant human mesothelin (Glu296-Gly580) produced by using human HEK293 cells
Isotype:
Rabbit IgG
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human mesothelin (B) were surface stained with Rabbit anti-MSLN monoclonal antibody 1µg/ml (clone: DM71) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 3. FACS data of serially titrated Rabbit anti-MSLN monoclonal antibody (clone: DM71) on Hela cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 4. Affinity ranking of different Rabbit anti-MSLN mAb clones by titration of different concentration onto Hela cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 4. Affinity ranking of different Rabbit anti-MSLN mAb clones by titration of different concentration onto Hela cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.