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Antibodies

PE-conjugated Anti-ACVR2A antibody(15D6); IgG1 Chimeric mAb

Product Sizes
100 test
£895.00
12-90436-100TEST
About this Product
SKU:
12-90436
Additional Names:
ACVR2; ACTRII
translate.label.attr.clone:
15D6
Clonality:
Monoclonal
Extra Details:
This gene encodes a receptor that mediates the functions of activins; which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain; a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia; a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq; Jun 2013]
Host:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2[o]C-8[o]C for 6 months
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody