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Antibodies

Biotinylated Anti-CD47 antibody(DM49); Rabbit mAb

Product Sizes
100 µg
£1001.00
12-9039-B-100UG
About this Product
SKU:
12-9039-B
Additional Names:
CD47; MER6; IAP; OA3
translate.label.attr.clone:
DM49
Clonality:
Monoclonal
Extra Details:
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3; Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets; and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA; binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion; enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Format:
Liquid
Host:
Rabbit
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2 [o]C-8 [o]C for 6 months
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody