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Antibodies

Anti-ACE2 antibody(DM48); Rabbit mAb

Product Sizes
100 µg
£801.00
12-9038-100UG
About this Product
SKU:
12-9038
Additional Names:
ACE-2; ACEH; ACE2
translate.label.attr.clone:
DM48
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9; and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function; as well as fertility. In addition; the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Host:
Rabbit
Immunogen:
Recombinant human ACE2 (Gln18-Ser740) produced by using human HEK293 cells
Isotype:
Rabbit IgG
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2. FACS data of serially titrated Rabbit anti-ACE2 monoclonal antibody (clone: DM48) on Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 3. Affinity ranking of different Rabbit anti-ACE2 mAb clones by titration of different concentration onto Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 3. Affinity ranking of different Rabbit anti-ACE2 mAb clones by titration of different concentration onto Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.