Anti-Zika; Env (Clone ZIKA-4499)-Purified No Carrier Protein
Product Sizes
250µg
£680.00
12-8293-250UG
About this Product
- SKU:
- 12-8293
- Additional Names:
- envelope; E protein
- translate.label.attr.clone:
- ZIKA-4499
- Clonality:
- Monoclonal
- Extra Details:
- Specificity: Anti-Zika virus (Clone ZIKA-4499) is specific for Zika virus envelope (E) protein. Background: Zika virus (ZIKV) infection during pregnancy is a global public health problem 1; linked causally to severe fetal abnormalities 2. Prophylactic antibodies may prove useful in treating pregnant patients or for designing epitope-specific vaccines 1. ZIKV is a mosquito-transmitted flavivirus that encodes a single polyprotein with an ~11 kb positive-sense RNA open reading frame 1. The polyprotein is cleaved into seven non-structural (NS) proteins and three structural proteins (capsid (C); pre-membrane (prM); and envelope (E)). C forms a nucleocapsid. prM complexes with E to facilitate folding and prevent premature fusion to host membranes. E is responsible for viral assembly; attachment; entry; and fusion 1;3 and is a major target of neutralizing antibody research 3. Mature ZIKV virions incorporate 180 copies each of the E and M proteins 4;5.
- Host:
- Mouse
- Isotype:
- Mouse IgG2a k
- Purification:
- Purity: >90% for SDS PAGE Preparation: This monoclonal antibody is purified by ion exchange chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- This purified antibody is stable when stored at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
