Anti-West Nile Virus Envelope Protein (Intermediate Domain) (WNV Env)
Product Sizes
20 µg
£500.00
12-8278-20UG
0.1 mg
£856.00
12-8278-0.1MG
About this Product
- SKU:
- 12-8278
- Clonality:
- Polyclonal
- Extra Details:
- Specificity: Rabbit Anti-West Nile Virus Envelope Protein (WNV Env) recognizes an epitope in the intermediate domain of WNV Env. This polyclonal antibody was purified using affinity chromatography. Background: West Nile Virus (WNV) is a member of the Flaviviridae; a plus-stranded virus family that includes St. Louis encephalitis virus; yellow fever virus; and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa; Asia; and Europe. It has rapidly spread across the United States with cases being observed in every continental state (reviewed in 1). Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins.1 While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway;2 the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein.3 The WNV receptor has recently been identified as alpha v beta 3 integrin.4
- Host:
- Rabbit
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- This polyclonal antibody is stable for at least one week when stored at 2-8[o]C. For long term storage; aliquotin woring volumes without diluing and store at 20[o]C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
