Anti-Shigella flexneri?2a; LPS (SHIG-8964)
Product Sizes
250µg
£680.00
12-8265-250UG
About this Product
- SKU:
- 12-8265
- translate.label.attr.clone:
- SHIG-8964
- Clonality:
- Monoclonal
- Extra Details:
- Specificity: Anti-Shigella flexneri (Clone SHIG-8964) is specific for the LPS of Shigella flexneri 2a and displays no cross reactivity for Shigella flexneri 1a; 3a; 4a; 5a; 6; S. sonnei; S. dysenteriae; S. boydii; Citrobacter; Salmonella (mix) or E. coli (mix). Background: Shigella flexneri serotype 2a is a specific strain of Shigella flexneri responsible for causing shigellosis; a prominent global gastrointestinal infection. Serotype 2a holds clinical importance due to its prevalence and virulence. Shigella flexneri 2a infections often lead to severe symptoms such as bloody diarrhea; abdominal cramps; and fever1. The lipopolysaccharides (LPS) on the bacterial cell surface play a pivotal role in its pathogenicity by contributing to adhesion; immune evasion; and triggering inflammatory responses in the host. The bacterium's ability to invade the colonic epithelium leads to localized inflammation and tissue damage; causing the characteristic symptoms of shigellosis. Recently; there have been reports of increased transmission of extensively drug-resistant (XDR) Shigella spp. through sexual activity2.
- Host:
- Mouse
- Isotype:
- Mouse IgG1
- Purification:
- Purity: ≥90% Preparation: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- This purified antibody is stable when stored at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Toxins
- Manufacturer's Data Sheet:download_pdf.php
