Anti-SARS-CoV-1; Spike RBD (Clone COV1-58)-Purified No Carrier Protein
Product Sizes
250 µg
£583.00
12-8261-250UG
1 mg
£812.00
12-8261-1MG
About this Product
- SKU:
- 12-8261
- translate.label.attr.clone:
- COV1-58
- Clonality:
- Monoclonal
- Extra Details:
- Specificity: COV1-58 targets the receptor-binding domain (RBD) of the SARS-CoV-1 prefusion spike protein (S2); located on the viral surface. Antigen Distribution: Anti-SARS-CoV-1 recognizes antigens on infected cells; including respiratory epithelial cells. Background: SARS-CoV-1; also known as the Severe Acute Respiratory Syndrome coronavirus; is a zoonotic virus that is believed to have originated from an animal reservoir; possibly horseshoe bats; and transmitted to humans1. This virus primarily affects the respiratory system and can cause symptoms such as muscle pain; headache; fever; cough; dyspnea; and pneumonia1;2. It was the first severe and readily transmissible new disease to emerge in the 21st century; with the capacity to spread globally via international air travel. COV1-58 is a monoclonal antibody that specifically targets the receptor-binding domain (RBD) of the SARS-CoV-1 spike protein. This antibody does not block the ACE2 receptor directly but serves as a neutralizer by preventing the virus from entering host cells. By binding to the RBD; COV1-58 likely interferes with the spike protein's ability to engage with the ACE2 receptor; thus neutralizing the virus. Its specificity for the RBD makes COV1-58 a crucial tool in neutralizing SARS-CoV-1 and offers potential in therapeutic applications; including the design of antibody cocktails to improve treatment efficacy.
- Isotype:
- Human IgG1Lambda
- Purification:
- Purity: >=90% monomer by analytical SEC and SDS-Page Preparation: Recombinant antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are pu
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- This antibody may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
