Anti-Respiratory Syncytial Virus (Clone: RSV-3M3)
Product Sizes
100 µg
£649.00
12-8119-100UG
About this Product
- SKU:
- 12-8119
- Additional Names:
- RSV; Orthopneumovirus.
- translate.label.attr.clone:
- RSV-3M3
- Clonality:
- Monoclonal
- Extra Details:
- Reactivity Species : Respiratory Syncytial-Virus Expression Host : HEK-293 Endotoxin Level :≤ 1.0 EU/mg as determined by the LAL method. Specificity : RSV-3M3 activity is directed against antigenic site IV of the RSV fusion (F) protein and binds to pre- and post-fusion F proteins of RSV A strain A2 and RSV B strain 18537. Clone RSV-3M3 is potent at neutralizing RSV A2; RSV Long viruses (subgroup A); RSV 18537 B; and RSV WV/401R viruses (subgroup B). Competition-binding assay shows that RSV-3M3 targets antigenic site IV. Mutagenesis experiments have revealed RSV-3M3 requires arginine residue R429 for binding and neutralization. EM reconstruction shows that RSV-3M3 binds close to a 0° tilt. RSV-3M3 does not neutralize hMPV.
- Host:
- Human
- Immunogen:
- Human donors targeting the post-fusion RSV F protein using human hybridoma technology.
- Isotype:
- Human IgG1
- Purification:
- >=95% monomer by analytical SEC
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Functional grade preclinical antibodies may be stored sterile as received at 2-8[o]C for up to one year. For longer term storage; aseptically aliquot in working volumes without diluting and store at >= -70[o]C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Viral Particles
- Manufacturer's Data Sheet:download_pdf.php
