Recombinant Anti-Monkeypox A33 Antibody (Clone: MPXV-56)
Product Sizes
100 µg (mg/mL)
£649.00
12-8114-100UG
About this Product
- SKU:
- 12-8114
- Additional Names:
- MPXV
- translate.label.attr.clone:
- MPXV-56
- Clonality:
- Monoclonal
- Extra Details:
- Expression Host : HEK-293 Endotoxin Level :≤ 1.0 EU/mg as determined by the LAL method Specificity : Clone MPXV-56 is reactive against A33; a surface antigen on the EV form of the virus; and is of the IgG2 isotype. Complementary screening approaches were used to identify orthopoxvirus-specific mAbs to MPXV; cowpox virus (CPXV); variola virus (VARV); and vaccinia virus (VACV). MPXV-56 is reactive against VACV antigen and lysate; CPXV lysate; MPXV lysate; and VARV antigen and lysate. MPXV-56 binds to VACV and VARV purified antigen and weakly binds virus-infected cell lysates of VACV; CPXV; and MPXV. MPXV-56 neutralizes VACV EV plus complement (+C') but not MV; MV+C'; or EV. MPXV-56 also neutralizes CPXV EV+C' but not EV and weakly neutralizes MPXV EV+C' but not MV; MV+C'; or EV.
- Host:
- Human
- Immunogen:
- MPXV-56 was generated from peripheral blood mononuclear cells obtained from donors who had either recovered from naturally-occurring MPXV infection or been immunized against vaccinia.
- Isotype:
- Human IgG1
- Purification:
- >=95% monomer by analytical SEC
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Functional grade preclinical antibodies may be stored sterile as received at 2-8[o]C for up to one year. For longer term storage; aseptically aliquot in working volumes without diluting and store at >= -70[o]C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:download_pdf.php
