Anti-Human IL-6 (Sarilumab) Fc Muted
Product Sizes
100 µg
£760.00
12-8090-100UG
About this Product
- SKU:
- 12-8090
- Additional Names:
- Interleukin-6; CDF; HGF; HSF; BSF2; BSF-2; IFNB2; IFN-beta-2
- translate.label.attr.clone:
- Hu137
- Clonality:
- Monoclonal
- Extra Details:
- Expression Host : HEK-293 Pathogen Testing : To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens; all of this recombinant biosimilar antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Sarilumab. Sarilumab binds to the transmembrane and soluble forms of the IL-6 receptor. This product is for research use only. IL-6 and its signaling pathway play a part in immune response regulation; inflammation; and hematopoiesis.2 Sarilumab is a research-grade recombinant human monoclonal IL-6 receptor antagonist. It specifically binds to both the transmembrane and soluble forms of the IL-6 receptor; thus inhibiting IL-6mediated cis and trans-signaling in a dose-dependent manner.1 Therapeutic Sarilumab; also known by the trade name Kevzara; is currently used to treat Rheumatoid Arthritis1; however; as of March 2020; The Feinstein Institute of Northwell Health publicized a study on a human antibody that may prevent the activity" of IL-6 for the treatment of COVID-19.3 Anti-Human IL-6 (Sarilumab) utilizes the same variable regions from the therapeutic antibody Sarilumab making it ideal for research projects."
- Host:
- Human
- Isotype:
- Human IgG1k
- Purification:
- >=95% monomer by analytical SEC
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Functional grade biosimilar antibodies may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at -80[o]C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
