Anti-Human IL-6 (Sarilumab) Biotin

Product Sizes

100 µg

£760.00

12-8086-100UG

About this Product

SKU:: 12-8086
Additional Names:: Interleukin-6; CDF; HGF; HSF; BSF2; BSF-2; IFNB2; IFN-beta-2
translate.label.attr.clone:: Hu137
Clonality:: Monoclonal
Extra Details:: Expression Host : HEK-293 This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Sarilumab. Sarilumab binds to the transmembrane and soluble forms of the IL-6 receptor. This product is for research use only. IL-6 and its signaling pathway play a part in immune response regulation; inflammation; and hematopoiesis.2 Sarilumab is a research-grade recombinant human monoclonal IL-6 receptor antagonist. It specifically binds to both the transmembrane and soluble forms of the IL-6 receptor; thus inhibiting IL-6mediated cis and trans-signaling in a dose-dependent manner.1 Therapeutic Sarilumab; also known by the trade name Kevzara; is currently used to treat Rheumatoid Arthritis1; however; as of March 2020; The Feinstein Institute of Northwell Health publicized a study on a human antibody that may prevent the activity" of IL-6 for the treatment of COVID-19.3 Anti-Human IL-6 (Sarilumab) utilizes the same variable regions from the therapeutic antibody Sarilumab making it ideal for research projects."
Host:: Human
Isotype:: Human IgG1k
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: This biotinylated antibody is stable when stored at 2-8[o]C. Do not freeze.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

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