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Antibodies

Anti-Human IL 12/23 (Briakinumab) PE

Product Sizes
50 µg
£594.00
12-8074-50UG
About this Product
SKU:
12-8074
Additional Names:
IL-12p40; Interleukin 12; Interleukin 23; IL12; IL23; IL-12; IL-23
translate.label.attr.clone:
ABT-874
Clonality:
Monoclonal
Extra Details:
Expression Host : HEK-293This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Briakinumab. Briakinumab recognizes both human IL12 and IL23 via IL-12/23p40. This product is for research use only.Briakinumab is a human monoclonal antibody targets the p40 subunit shared by interleukins 12 and 23. IL-12 associates with IL-23alpha to form the heterodimeric cytokine IL-23. IL-23 is associated with various autoimmune inflammatory diseases; and is particularly highly expressed in psoriasis skin lesions. In addition; IL-23 is suspected to play a role in tumorigenesis. Briakinumab binds to and neutralizes human IL-12 and IL-23 (via their shared p40 subunit) and is being investigated for the treatment of rheumatoid arthritis; inflammatory bowel disease; and multiple sclerosis. Anti-Human IL 12/23 (Briakinumab) utilizes the same variable regions from the therapeutic antibody Briakinumab making it ideal for research projects.
Host:
Human
Immunogen:
This antibody was produced by phage display technology.
Isotype:
Human IgG1lambda
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
This R-phycoerythrin (R-PE) conjugate is stable when stored at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody