Anti-Human DR5 (Drozitumab) Fc Muted
Product Sizes
100 µg
£760.00
12-8065-100UG
About this Product
- SKU:
- 12-8065
- Additional Names:
- DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
- translate.label.attr.clone:
- PRO95780
- Clonality:
- Monoclonal
- Extra Details:
- Expression Host : HEK-293 Pathogen Testing : To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens; all of this recombinant biosimilar antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Drozitumab. Clone PRO95780 recognizes human death receptor 5 (DR5). This product is for research use only. Drozitumab is a monoclonal antibody that specifically binds to human DR5. DR5 is expressed in a variety of solid tumors and hematologic malignancies; which are characteristically resistant to apoptosis. Drozitumab is a proapoptotic receptor agonists (PARA) that induces apoptosis in a variety of human cancer cell lines and xenograft models; both alone and in tandem with other antineoplastic agents.1 Apoptosis of cancer cells triggered by the activation of DR5; occurs without affecting most normal cell types. Anti-Human DR5 (Drozitumab) utilizes the same variable regions from the therapeutic antibody Drozitumab making it ideal for research projects.
- Host:
- Human
- Immunogen:
- DR5 scFv
- Isotype:
- Human IgG1lambda
- Purification:
- >=95% monomer by analytical SEC
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Functional grade biosimilar antibodies may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at -80[o]C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
