Anti-Human CD11a (Efalizumab) Fc Muted
Product Sizes
100 µg
£760.00
12-8016-100UG
About this Product
- SKU:
- 12-8016
- Additional Names:
- ITGAL; integrin alpha L; LFA-1; LFA1A
- translate.label.attr.clone:
- hu1124
- Clonality:
- Monoclonal
- Extra Details:
- Expression Host : HEK-293 Pathogen Testing : To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens; all of this recombinant biosimilar antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Efalizumab. Clone hu1124 recognizes human CD11a. This product is for research use only. CD11a and CD18 are the Integrin alpha-L and beta-2 subunits that combine to form LFA-1; a glycoprotein and a member of the Integrin family. The Integrin alpha-L/beta-2 complex is a receptor for ICAM1; ICAM2; ICAM3; ICAM4 and F11R. LFA-1 participates in the immunological synapses between CD8+ T lymphocytes and antigen-presenting cells. Efalizumab binds to the CD11a subunit of LFA-1 and acts as an immunosuppressant by inhibiting lymphocyte activation and cell migration out of blood vessels into tissues. Anti-Human CD11a (Efalizumab) utilizes the same variable regions from the therapeutic antibody Efalizumab making it ideal for research projects.
- Host:
- Human
- Immunogen:
- Human CD11a
- Isotype:
- Human IgG1k
- Purification:
- >=95% monomer by analytical SEC
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Functional grade biosimilar antibodies may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at -80[o]C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
