Phospho-MARCKS (Ser167/170) (Clone: C9) rabbit mAb APC conjugate
Product Sizes
10 Tests
£532.00
12-4340-10TESTS
100 Tests
£792.00
12-4340-100TESTS
About this Product
- SKU:
- 12-4340
- Additional Names:
- Myristoylated alanine-rich C-kinase substrate; Protein kinase C substrate; PKCSL; 80 kDa protein light chain; MACS; PRKCSL
- translate.label.attr.clone:
- MARCKSS167170-C9
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- MARCKS (myristoylated alanine-rich C kinase substrate) is a major PKC substrate expressed in all eukaryotic cells(1;2). It binds to and cross-links actin filaments to serve as a bridge between Ca2+/calmodulin and PKC signaling and attenuates phosphatidylinositol 4;5-bisphosphate plasma membrane signaling (3). MARCKS is involved with cell mobility; phagocytosis; membrane traffic; cell adhesion; and mitogenesis. Ser159; 163; 167 and 170 of MARCKS are phosphorylated by PKC in response to cell groeth and cellular stress (4). MARCKs phosphorylation is believe to induce its tranlocation from plasma membrane to cytoplasm.
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS
- Isotype:
- Rabbit IgG1k
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
