Phospho-mTOR (Ser2448) (Clone: E11) rabbit mAb
Product Sizes
20 µl
£631.00
12-4295-20UL
200 µl
£1021.00
12-4295-200UL
About this Product
- SKU:
- 12-4295
- Additional Names:
- Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1; FRAP; FRAP1; FRAP2; RAFT1; RA
- translate.label.attr.clone:
- mTORS2448-E11
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Extra Details:
- mTOR; mammalian target of rapamycin; is a Serine/Threonine protein kinase (1-2) that functions as an amino acid and ATP sensor to balance cell growth and nutrient availability (3-4). When sufficient nutrients are available; mTOR transmits a positive signal to p70 S6 kinase and participates in the inactivation of 4E-BP1 (5). mTOR plays a key role in homeostasis and cell growth; and phospho mTOR may be abnormally regulated in tumors. mTOR is a potential target for anti-cancer therapy (6).
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR
- Isotype:
- Rabbit IgG1k
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
