Phospho-MKK3 (S189)/MKK6 (S207) (Clone: D3) rabbit mAb PE conjugate
Product Sizes
10 Tests
£532.00
12-4221-10TESTS
100 Tests
£792.00
12-4221-100TESTS
About this Product
- SKU:
- 12-4221
- Additional Names:
- Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3; MAPK/ERK kinase 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK2; MAP2K3; MEK3; PRKMK3; SKK2
- translate.label.attr.clone:
- MKK3S189MKK6S207-D3
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- MKK3 and MKK6 are closely related dual-specificity protein kinases that activate p38 MAP kinase (1-5). Phospho MKK3 and phospho MKK6 both phosphorylate and activate p38. p38 phosphorylation dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines (4;5). Phospho MKK3 and phospho MKK6 activation occurs through phosphorylation at S189 and T222 on MKK3 (2) and S207 and T211 on MKK6 (4;5).
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6.
- Isotype:
- Rabbit IgG1k
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
