Phospho-Histone H2A.X (Ser139) (Clone: 1B3) rabbit mAb PE conjugate
Product Sizes
10 Tests
£532.00
12-4206-10TESTS
100 Tests
£792.00
12-4206-100TESTS
About this Product
- SKU:
- 12-4206
- Additional Names:
- H2AFX; H2AX; ?H2AX; gamma-H2AX
- translate.label.attr.clone:
- HisH2AXS139-1B3
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- Histone H2AX is a variant of the nucleosome core histone H2A and is phosphorylated at Ser139 in response to DNA damage. Histone H2AX phosphorylation is considered a specific reporter of double-strand DNA breaks. The protein is also referred to as gH2AX when phosphorylated at Ser139. H2AX phosphorylation is especially strong in response to double-strand breaks formed during apoptosis. However; physiological phosphorylation of Histone H2AX occurs when double-strand DNA breaks are formed during meiosis and V(D)J recombination. A549 and DU145 cell lines have been found to have higher expression levels of phosphorylated Histone H2AX compared to Jurkat; MCF-7; or HL-60 cell lines.
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
- Isotype:
- Rabbit IgG1k
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
