Phospho-PI3 Kinase p85 (Tyr458)/p55 (Tyr199) (Clone: 1A11) rabbit mAb SureLight488 conjugate
Product Sizes
10 Tests
£532.00
12-4158-10TESTS
100 Tests
£792.00
12-4158-100TESTS
About this Product
- SKU:
- 12-4158
- Additional Names:
- Phosphatidylinositol 3-kinase regulatory subunit alpha; PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit beta; PIK3R2; Phosphatidylinositol 3-kinase regulatory subunit gamma; PIK3R3; p55PIK
- translate.label.attr.clone:
- PI3KY458-1A11
- Clonality:
- Monoclonal
- Conjugate:
- SureLight 488
- Extra Details:
- Phosphoinositidine 3-kinase (PI3K) targets phosphoinositide lipids for phosphorylation at the D-3 position to serve as a second messenger molecule to activate signaling pathways in response to extracellular stimuli. Akt/protein kinase B (PKB) is a major downstream target of PI3K. The multiple forms of PI3K have different specificities and different affinities for various phosphatidylinositol forms. The PH domains of downstream proteins in these pathways bind to these secondary messengers; causing altered cellular distribution and subsequent kinase activation. The PI3K/Akt pathway is altered in a large proportion of human cancers; as this pathway regulates cellular survival; cell cycle progression; and cell growth.
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Tyr458 of human phospho PI3K p85
- Isotype:
- Rabbit IgG1k
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
