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Antibodies

Anti-PD-1(Opdivo)(Nivolumab biosimilar) mAb

Product Sizes
100 µg
£759.00
12-2001-100UG
About this Product
SKU:
12-2001
Clonality:
Monoclonal
Extra Details:
Nivolumab (Optivo); Pembrolizumab are both PD-1 inhibitors. PD-1 is a checkpoint" protein on immune cells that alerts them not to attack cells that express PD-L1. Some cancer cells express PD-L1; which enables them to “switch off” an immune system response. Monoclonal antibodies such as pembrolizumab and nivolumab block this signaling between PD-1 and PD-L1 and thereby reinforce the immune system response to tumor cells.
Isotype:
IgG4
Purification:
Purified from cell culture supernatant by affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C (Avoid repeated freezing and thawing).
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Flow Cytometry analysis: Anti-PD-1 (Opdivo) binds on the cell surface of PD-1 stable cell line (Cat No. 14-500ACL) using 0.5 ug of antibody. Green represents Anti-human IgG isotype control; red represents Anti-PD-1 (Opdivo)(Nivolumab biosimilar). FITC conjugated Goat anti-Human Fc was used as secondary antibody.
Figure 2: Flow Cytometry analysis: Anti-PD-1 (Opdivo) binds on the cell surface of PD-1 stable cell line (Cat No. 14-500ACL) using 0.5 ug of antibody. Green represents Anti-human IgG isotype control; red represents Anti-PD-1 (Opdivo)(Nivolumab biosimilar). FITC conjugated Goat anti-Human Fc was used as secondary antibody.