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Antibodies

Anti-TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (Clone:NX2.1/1855R)

Product Sizes
20 µg
£408.00
12-1260-20UG
100 µg
£716.00
12-1260-100UG
About this Product
SKU:
12-1260
Additional Names:
BCH; Benign chorea; BHC; Homeobox protein Nkx2.1; NK2 homeobox 1; NKX2.1; NKX2A; TEBP; Thyroid nuclear factor-1; Thyroid specific enhancer binding protein; Thyroid transcription factor-1 (TTF-1); Tin man; TITF1; TTF-1
translate.label.attr.clone:
NX2.1/1855R
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 40kDa; identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver; stomach; pancreas; small intestine; colon; kidney; breast; skin; testes; pituitary; prostate; and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast; mediastinal germ cell tumors; and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Format:
Purified
Host:
Rabbit
Immunogen:
Recombinant full-length TTF-1 protein
Isotype:
Rabbit IgG
Purification:
Protein A/G
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg