Anti-TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rNX2.1/690)
Product Sizes
20 µg
£408.00
12-1259-20UG
100 µg
£716.00
12-1259-100UG
About this Product
- SKU:
- 12-1259
- Additional Names:
- BCH; Benign chorea; BHC; Homeobox protein Nkx2.1; NK2 homeobox 1; NKX2.1; NKX2A; TEBP; Thyroid nuclear factor-1; Thyroid specific enhancer binding protein; Thyroid transcription factor-1 (TTF-1); Tin man; TITF1; TTF-1
- translate.label.attr.clone:
- rNX2.1/690
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 40kDa; identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver; stomach; pancreas; small intestine; colon; kidney; breast; skin; testes; pituitary; prostate; and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast; mediastinal germ cell tumors; and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length TTF-1 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
