Anti-TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) Recombinant Rabbit Monoclonal Antibody (Clone:VEGI/2052R)
Product Sizes
20 µg
£408.00
12-1256-20UG
100 µg
£716.00
12-1256-100UG
About this Product
- SKU:
- 12-1256
- Additional Names:
- TNF ligand-related molecule 1 (TL1A); Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15); Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI); VEGI192A
- translate.label.attr.clone:
- VEGI/2052R
- Clonality:
- Monoclonal
- Extra Details:
- VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily; member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells; but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases; and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation; and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human VEGI protein
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
