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Antibodies

Anti-Thrombomodulin / CD141 (Endothelial Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:rTHBD/1591)

Product Sizes
20 µg
£408.00
12-1247-20UG
100 µg
£716.00
12-1247-100UG
About this Product
SKU:
12-1247
Additional Names:
AHUS6; BDCA3; CD141; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin (TM)
translate.label.attr.clone:
rTHBD/1591
Clonality:
Monoclonal
Extra Details:
It recognizes a protein of 75kDa; identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells; such as endothelial and mesothelial cells. In addition; synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma; angiosarcoma; and epithelioid hemangioendothelioma). Hence; anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently; thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.i
Format:
Purified
Host:
Mouse
Immunogen:
Recombinant fragment of human Thrombomodulin protein (around aa 69-194) (exact sequence is proprietary)
Isotype:
Mouse IgG1; kappa
Purification:
Protein A/G
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Formalin-fixed; paraffin-embedded human Placenta stained with Thrombomodulin / CD141 Monoclonal Antibody (rTHBD/1591).
Figure 3:SDS-PAGE Analysis Purified Thrombomodulin Mouse Recombinant Monoclonal Antibody (rTHBD/1591).
Figure 4:Analysis of Protein Array containing >19;000 full-length human proteins using Thrombomodulin Recombinant Mouse Monoclonal Antibody (rTHBD/1591) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated
Figure 4:Analysis of Protein Array containing >19;000 full-length human proteins using Thrombomodulin Recombinant Mouse Monoclonal Antibody (rTHBD/1591) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated