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Antibodies

Anti-Parathyroid Hormone (PTH) (N-Terminal) Recombinant Rabbit Monoclonal Antibody (Clone:PTH/2295R)

Product Sizes
20 µg
£408.00
12-1235-20UG
100 µg
£716.00
12-1235-100UG
About this Product
SKU:
12-1235
Additional Names:
hPTH; Parathormone; Parathyrin; Parathyroid hormone 1 (PTH1); Parathyroid hormone (PTH)
translate.label.attr.clone:
PTH/2295R
Clonality:
Monoclonal
Extra Details:
Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.iIt is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation; as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures; tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Format:
Purified
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to amino acids around 1 to 34 of mature PTH conjµgated to a carrier
Isotype:
Rabbit IgG
Purification:
Protein A/G
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg