Anti-NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) Recombinant Mouse Monoclonal Antibody (Clone:rNX2/1523)
Product Sizes
20 µg
£408.00
12-1225-20UG
100 µg
£716.00
12-1225-100UG
About this Product
- SKU:
- 12-1225
- Additional Names:
- Homeobox protein NK-2 homolog B; NK2 transcription factor like protein B; NK2 transcription factor related locus 2; NKX22; Nkx2b; tinman
- translate.label.attr.clone:
- rNX2/1523
- Clonality:
- Monoclonal
- Extra Details:
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut; making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently; NKX2.2 protein was identified as a target of EWS-FLI-1; the fusion protein specific to Ewing sarcoma; and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma; with a sensitivity of 93% and a specificity of 89%; and aids in the differential diagnosis of small round cell tumors.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human NKX2.2 protein (around aa 1-119) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
