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Antibodies

Anti-MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (Clone:MUC1/2278R)

Product Sizes
20 µg
£408.00
12-1215-20UG
100 µg
£716.00
12-1215-100UG
About this Product
SKU:
12-1215
Additional Names:
Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PE
translate.label.attr.clone:
MUC1/2278R
Clonality:
Monoclonal
Extra Details:
This MAb reacts with MUC1; a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved; O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sµgar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.
Format:
Purified
Host:
Rabbit
Immunogen:
Human milk-fat globule membranes (HMFGM)
Isotype:
Rabbit IgG
Purification:
Protein A/G
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg