Anti-MMP3 Recombinant Rabbit Monoclonal Antibody (Clone:MMP3/1994R)
Product Sizes
20 µg
£408.00
12-1210-20UG
100 µg
£716.00
12-1210-100UG
About this Product
- SKU:
- 12-1210
- Additional Names:
- CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1
- translate.label.attr.clone:
- MMP3/1994R
- Clonality:
- Monoclonal
- Extra Details:
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components; including collagen; gelatin; fibronectin; laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester; lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3; MMP-10 and MMP-11 (also designated stromelysin-1; 2 and 3; respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine; and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment of human MMP3 protein (around aa 317-327) (exact sequence is proprietary)
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
