Anti-FOXA1 / HNF3A Recombinant Mouse Monoclonal Antibody (Clone:rFOXA1/1515)
Product Sizes
20 µg
£408.00
12-1182-20UG
100 µg
£716.00
12-1182-100UG
About this Product
- SKU:
- 12-1182
- Additional Names:
- Forkhead box protein A1 (FOXA1); Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A); Transcription factor 3A (TCF-3A or TCF3A)
- translate.label.attr.clone:
- rFOXA1/1515
- Clonality:
- Monoclonal
- Extra Details:
- The transcription factor Forkhead-box A1 (FOXA1); also known as hepatocyte nuclear factor 3-alpha; is a member of the FOX class of transcription factors.HNF-1 ( and ); HNF-3 (; and ); HNF-4 ( and ); and HNF-6 compose; in part; a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney; small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs; such as lung; pancreas; bladder; prostate; and colon. Recently; FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity; especially in luminal subtype A breast cancers; which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human FOXA1 protein (around aa 372-472) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
