Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (Clone:FLG/1957R)
Product Sizes
20 µg
£408.00
12-1181-20UG
100 µg
£716.00
12-1181-100UG
About this Product
- SKU:
- 12-1181
- Additional Names:
- ATOD2; Epidermal Filaggrin; Filaggrin; Filaggrin precursor; Fillagrin; FLG; Profilaggrin
- translate.label.attr.clone:
- FLG/1957R
- Clonality:
- Monoclonal
- Extra Details:
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor; profilaggrin (consisting of multiple filaggrin units of 324 aa each); which is localized in keratohyalin granules; and is subsequently proteolytically processed into individual functional filaggrin molecules.iActive filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer; sµggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment of human Filaggrin protein (aa 198-288) (exact sequence is proprietary)
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
