Anti-E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) Recombinant Rabbit Monoclonal Antibody (Clone:CDH1/2208R)
Product Sizes
20 µg
£408.00
12-1171-20UG
100 µg
£716.00
12-1171-100UG
About this Product
- SKU:
- 12-1171
- Additional Names:
- Arc 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD324; CDH1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependent adhesion protein; Liver cell adhesion molecule (LCAM); Uvomorulin (UVO)
- translate.label.attr.clone:
- CDH1/2208R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 120-80kDa; identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins; E-; N- andP-cadherin; consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins; such as catenin; to regulate cadherin function.E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer; prostate and esophageal cancer. In combination with p120 Catenin; it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human E-Cadherin protein
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
