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Antibodies

Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rKRT10/844)

Product Sizes
20 µg
£408.00
12-1150-20UG
100 µg
£716.00
12-1150-100UG
About this Product
SKU:
12-1150
Additional Names:
BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
translate.label.attr.clone:
rKRT10/844
Clonality:
Monoclonal
Extra Details:
This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
Format:
Purified
Host:
Mouse
Immunogen:
Recombinant full-length human KRT10 protein
Isotype:
Mouse IgG1; kappa
Purification:
Protein A/G
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg