Anti-CD86 (Dendritic Cells Maturation Marker) Recombinant Mouse Monoclonal Antibody (Clone:rC86/1146)
Product Sizes
20 µg
£408.00
12-1131-20UG
100 µg
£716.00
12-1131-100UG
About this Product
- SKU:
- 12-1131
- Additional Names:
- Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2
- translate.label.attr.clone:
- rC86/1146
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 70kDa; which is identified as CD86. CD86is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86; along with CD80/B71; is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction; it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human CD86 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
