Anti-CD45 / LCA (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody (Clone:PTPRC/1975R)
Product Sizes
20 µg
£408.00
12-1123-20UG
100 µg
£716.00
12-1123-100UG
About this Product
- SKU:
- 12-1123
- Additional Names:
- B220; CD45R; GP180; Leukocyte common antigen (LCA); Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC); Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
- translate.label.attr.clone:
- PTPRC/1975R
- Clonality:
- Monoclonal
- Extra Details:
- CD45R; also designated CD45 and PTPRC; has been identified as a transmembrane glycoprotein; broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throµghout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4; 5; and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4); CD45RB (exon 5); CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R; while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Human recombinant full-length CD45 protein
- Isotype:
- Rabbit IgG
- Purification:
- Protein A/G
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
